A message from Eggers about a possible visual sprite issue that may arise from using these patches, or just editing RotDS character sprites in general, due to his extended palette code that is implemented in RotDS:

Eggers: "When you are actively using these alternate character sprite patches, you may encounter a problem -- if you save a game (or save a state), and then use a patch or edit the ROM to change a character sprite, and then subsequently load the game which you saved while using the old sprite data, your new sprites may not show up with correct colors.

A fix is available in-game. If you're experiencing this problem, open the main menu (the one that shows character portraits and has options for items, skills, equip, and so on). Hold down the L and R buttons, and press SELECT. This will clear a cache of data, which is responsible for the issue. If cached data is found and cleared, you will hear a tone (the "healing" sound-effect).

The next time you enter battle, your new sprites will display correctly. You may notice a short pause as the data is recalculated. That will only happen the first time a sprite is used in battle after the cache is cleared, once for each sprite."